NCT06723041

Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

Acupressure for Anxiety: A Randomized Controlled Trial of an Acupressure Intervention for Patients Receiving Cancer-Directed Therapy

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinicaI trial is being done to determine if acupressure is helpful to reduce anxiety related to chemotherapy, compared with "sham" (or placebo) acupressure in patients with cancer. Anxiety, experienced by many patients with cancer, can be related to chemotherapy and may contribute to other symptoms, such as nausea and poor quality of life. Some patients diagnosed with cancer express interest in non-medicine ways to manage symptoms. Acupressure is the application of non-invasive finger pressure along energy points throughout the body in order to relieve pain and induce a feeling of well-being. Previous research has shown that acupressure can help both adults and children with their anxiety in certain situations, such as after surgery. Patients can be taught how to do the acupressure on themselves, making this an intervention that can be done anywhere. Acupressure is well tolerated with minimal reports of adverse reactions. Undergoing acupressure may be effective in reducing anxiety in cancer patients receiving chemotherapy.

Detailed description

PRIMARY OBJECTIVE: I. To test the efficacy of a nurse-applied acupressure intervention for anxiety associated with active cancer-directed therapy. SECONDARY OBJECTIVES: I. To test the efficacy of a patient-applied acupressure intervention for anxiety associated with active cancer-directed therapy. II. To assess whether acupressure appears to improve nausea related to cancer and cancer-directed therapy. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients undergo true acupressure over 10 minutes on study. Patients that choose to learn self-administration acupressure at home receive educational information and undergo self-administration acupressure sessions at least twice daily (BID) for seven days. ARM II: Patients undergo sham acupressure over 10 minutes on study. Patients that choose to learn self-administration acupressure at home receive educational information and undergo self-administration acupressure sessions at least BID for seven days.

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
PROCEDURE	Acupressure Therapy	Undergo true acupressure
PROCEDURE	Acupressure Therapy - placebo	Undergo sham acupressure
PROCEDURE	Acupressure Therapy - self-administered	Undergo self-administered acupressure
OTHER	Health Promotion and Education	Receive educational handouts
OTHER	Survey Administration	Ancillary studies

Timeline

• Start date: 2024-12-11
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2024-12-09
• Last updated: 2025-12-30

Locations

1 site across 1 country: United States