Trials / Completed
CompletedNCT06722430
A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants
A Phase 1 Open-label Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Icalcaprant in Healthy Adult Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- AbbVie · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study is to assess the change of itraconazole, a strong CYP3A inhibitor, on the pharmacokinetics, safety, and tolerability of a single dose of icalcaprant in healthy participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Icalcaprant | Oral capsule |
| DRUG | Itraconazole (ITZ) | Oral capsule |
Timeline
- Start date
- 2024-11-13
- Primary completion
- 2025-01-13
- Completion
- 2025-01-13
- First posted
- 2024-12-09
- Last updated
- 2025-01-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06722430. Inclusion in this directory is not an endorsement.