NCT06721416

Comparing the Acute Effects of Different Exercise Approaches in Patients With Multiple Sclerosis

Comparing the Acute Effects and Cortical Hemodynamic Response of Different Exercise Approaches in Patients With Multiple Sclerosis: fNIRS Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Acibadem University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

Multiple Sclerosis (MS) is the second most common neurological disorder in young adults after trauma. Treatments developed today can slow progression and reduce symptoms. Exercise therapy is a useful rehabilitation practice in MS to manage symptoms, restore function, optimize quality of life, ensure well-being and increase participation in daily life activities. In this study, it is planned to investigate the acute effects of conservative and virtual reality (VR)-based aerobic exercise applications and standard exercises that frequently form the rehabilitation programs of individuals with MS in clinics. For this purpose, patients with MS who met the inclusion criteria were given two-week intervals; Conservative aerobic exercise, virtual reality-based aerobic exercise and standard exercise practices will be performed. With the data obtained from this study, it is aimed to investigate the safety of aerobic exercises performed using VR tools that can be used in telerehabilitation applications, which are thought to have a very important place in MS rehabilitation in the future, in terms of acute body temperature increase, cognitive and physical fatigue caused by conservative methods and fNIRS cortical effects of VR-based aerobic exercise applications. It will be possible to prove it with objective methods such as.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
OTHER	Traditional Aerobic Exercise	Traditional aerobic exercise will be continued with an arm ergometer, at moderate intensity, for 30 minutes.
OTHER	VR Based Aerobic Exercise	In the virtual reality-based aerobic exercise training, the game called "Beat Saber" will be played with Oculus Quest 2 virtual reality for 30 minutes.
OTHER	Conventional Exercise	The conventional exercise program will be modified with stabilization, balance and strengthening exercises, taking into account the functional status of the participants.

Timeline

• Start date: 2024-12-01
• Primary completion: 2025-07-30
• Completion: 2025-08-30
• First posted: 2024-12-06
• Last updated: 2025-09-17

Locations

1 site across 1 country: Turkey (Türkiye)