NCT06720467

Immunotherapy in Eyelid Viral Papilloma

Role of Immunotherapy in the Treatment of Eyelid Viral Papilloma

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

intralesional injection of Candida antigens for treating eyelid warts is supposed to have less destructive effect than other surgical interventions

Detailed description

Despite many surgical and interventional modalities of treating ocular warts, all have a destructive nature for this delicate tissue with a high recurrence rate. intralesional injection of Candida antigens was suggested to be an effective and safe treatment for such a condition aim: Providing safe and effective treatment of ocular wart. objective: 1. To determine the efficacy of intralesional injection of Candida antigens in the treatment of eyelids wart 2. To determine the safety of intralesional injection of Candida antigens in the treatment of eyelids wart 3. To report complications of intralesional injection of Candida antigens in the treatment of eyelids wart

Conditions

• Eye Infections

Interventions

Type	Name	Description
BIOLOGICAL	Intralesional injection of Candida albicans 1:20 w/v 10 ml vial (Allergy Laboratories, INC. Oklahoma City, USA.)	Intralesional injection of 0.2 ml of 1/1000 solution of Candida albicans antigen using an insulin syringe directly into the warts; Candida albicans 1:20 w/v 10 ml vial (Allergy Laboratories, INC. Oklahoma City, USA.). The same injection was repeated every 2 weeks until complete clearance for a maximum of six treatment sessions.

Timeline

• Start date: 2024-06-11
• Primary completion: 2025-03-15
• Completion: 2025-06-15
• First posted: 2024-12-06
• Last updated: 2025-08-17

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study