NCT06720090

Light Therapy for Obsessive-compulsive Disorder (OCD)

Light Therapy for Obsessive-compulsive Disorder: A Circadian Medicine Approach

• Status: Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 17 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later). The main question\[s\] it aims to answer are: Does light therapy reduce OCD symptoms? Does light therapy advance the circadian clock? If there is a comparison group: Researchers will compare a higher dose of light therapy to a lower dose to see if dose amount affects symptom reduction. Participants will asked to: 1. Wear light therapy glasses for 1 hour each morning and complete a daily light therapy log for 5 weeks 2. Track their sleep every day with a wearable monitor and an electronic sleep diary for 5 weeks 3. Complete a 1-time assessment of sensitivity to light exposure 4. Complete self-report measures of OCD 4 times/day at baseline (2 weeks), mid-treatment (1 week), and end of treatment (1 week)

Conditions

• OCD

Interventions

Type	Name	Description
BEHAVIORAL	Light therapy	5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening.

Timeline

• Start date: 2024-12-16
• Primary completion: 2029-03-01
• Completion: 2029-03-01
• First posted: 2024-12-06
• Last updated: 2025-07-15

Locations

1 site across 1 country: United States