NCT06718985

Impact of Bone Mineral Density on Fracture Risk Assessment in RA

Does Incorporating Bone Mineral Density Change Fracture Risk Assessment and Influence Treatment Decisions in Rheumatoid Arthritis Patients?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Other Government
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: —

Summary

This study investigates whether incorporating bone mineral density (BMD) into FRAX calculations changes fracture risk assessment and influences treatment decisions in rheumatoid arthritis (RA) patients. Analyzing 60 RA patients, FRAX scores for 10-year major osteoporotic and hip fractures were calculated with and without BMD. While no significant differences were found between the two methods, discrepancies in treatment recommendations were identified, particularly for hip fractures. The findings emphasize the importance of combining BMD and FRAX for a more comprehensive fracture risk assessment and informed treatment decision-making in RA patients.

Conditions

• Rheumatoid Arthritis

Interventions

Type	Name	Description
OTHER	No intervention	No intervention

Timeline

• Start date: 2022-12-04
• Primary completion: 2023-04-04
• Completion: 2023-04-04
• First posted: 2024-12-05
• Last updated: 2024-12-05

Locations

1 site across 1 country: Turkey (Türkiye)