Trials / Recruiting
RecruitingNCT06713902
Extracellular Vesicles in Fibrin Gel for Cartilage Repair
Fibrin Gel Loaded with Extracellular Vesicles for the Treatment of Cartilage Lesions in the Joints - GelVex Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 51 (estimated)
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This project aims to produce and study in vitro/ex vivo a platelet rich plasma (PRP)-derived fibrin gel loaded with mesenchymal stromal cells (MSC)-extracellular vesicles (EVs), to combine the positive results on cartilage growth of PRP growth factors and the hyaline cartilage stimulating activity of MSC-EVs. Therefore, the project goal is to provide an advanced option for orthopedic patients with an innovative evolution of a gold standard procedure, making it easy to translate into daily clinical practice for physicians, healthcare professionals and patients.
Conditions
Timeline
- Start date
- 2024-10-29
- Primary completion
- 2026-08-30
- Completion
- 2026-08-30
- First posted
- 2024-12-03
- Last updated
- 2024-12-03
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06713902. Inclusion in this directory is not an endorsement.