NCT06710392

Efficacy of Two Enzyme Cocktails in Healthy Adults

Evaluate the Safety and Efficacy of Two Enzyme Cocktails in Healthy Adults With Subclinical Mild to Moderate Gastrointestinal Complaints

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: The Archer-Daniels-Midland Company · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to determine the safety and efficacy of two enzyme cocktails in healthy adults with mild to moderate gastrointestinal discomfort. The main question aims to answer whether a 4-week administration of an enzyme cocktail can improve how the participant feels about their gut health. This is done by completing a weekly questionnaire, and the results are compared between the 4 weeks the participants are on a placebo and the 4 weeks the participants are on the enzyme cocktail. Participants will also provide a stool sample at the start and end of each treatment. Stool samples will collected and stored in case further microbiome analysis is warranted.

Conditions

• Digestive
• Gastrointestinal Health

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Enzyme Cocktail A	Enzyme cocktail A in the form of a capsule with a daily dose of 275mg taken 3 times a day for 4 weeks.
DIETARY_SUPPLEMENT	Enzyme Cocktail B	Enzyme cocktail B in the form of a capsule with a daily dose of 50mg taken 3 times a day for 4 weeks.
DIETARY_SUPPLEMENT	Placebo A	Placebo A matching investigational product A given 3 times a day for 4 weeks.
DIETARY_SUPPLEMENT	Placebo B	Placebo B matching investigational product B given 3 times a day for 4 weeks.

Timeline

• Start date: 2024-12-15
• Primary completion: 2025-11-30
• Completion: 2025-11-30
• First posted: 2024-11-29
• Last updated: 2024-11-29

Locations

1 site across 1 country: United States