NCT06709534

An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors

Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Emory University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.

Detailed description

PRIMARY OBJECTIVES: I. To examine the feasibility and acceptability of an individualized home-based exercise program in gynecologic cancer survivors. II. To test the effect of the program on gut microbiome and psychoneurological symptoms in gynecologic cancer survivors. OUTLINE: Participants meet with a certified exercise trainer and complete a functional capacity assessment using a treadmill or 6-minute walk test. Participants then complete an individualized online home-based exercise intervention via Zoom consisting of progressive, moderate-intensity walking corresponding to the rate of perceived exertion (RPE) scale and receive social support over 30 minutes twice a week (BIW) for 12 weeks.

Conditions

• Malignant Female Reproductive System Neoplasm

Interventions

Type	Name	Description
OTHER	Exercise Intervention	Participate in an individualized online home-based exercise intervention
OTHER	Functional Assessment	Complete functional capacity assessment
OTHER	Medical Device Usage and Evaluation	Wear an activity tracker
OTHER	Questionnaire Administration	Ancillary studies
OTHER	Supportive Care	Receive social support

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-07-30
• Completion: 2027-07-30
• First posted: 2024-11-29
• Last updated: 2025-09-11

Locations

4 sites across 1 country: United States