NCT06705920

Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization

Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization : Randomized Controlled Clinical Trial

• Status: Active Not Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 44 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

To assess the antibacterial efficiency of oxygenated gel therapy on wound healing and microbiological colonization around surgical sutures

Detailed description

All the patients who will agree to participate in the study and who will sign the informed consent forms. Computer-generated randomization will be used to randomly divide the surgical sites into two groups. Control group: will receive no treatment. Study group: will receive active oxygen gel around suture. Patients scheduled for any oral surgical flap procedure that require suturing will be included in this study. After flap approximation, the surgical site will be sutured using 5-0 braided sutures. In the study group the gel will be applied over the suture and the patients will be instructed to apply the gel to the wound area and to the suture thread using a cotton swab, three times a day after brushing their teeth. Also, patients will be given instructions regarding their post-surgical care.

Conditions

• Patients Scheduled for Any Oral Surgical Flap Procedure That Require Suturing Will Be Included in This Study

Interventions

Type	Name	Description
DRUG	topical oxygen gel	In the study group the gel will be applied over the suture and the patients will be instructed to apply the gel to the wound area and to the suture thread using a cotton swab

Timeline

• Start date: 2024-11-01
• Primary completion: 2025-03-01
• Completion: 2025-06-01
• First posted: 2024-11-26
• Last updated: 2024-11-26

Locations

1 site across 1 country: Egypt