NCT06705647

Analyzing Acoustic Properties of the Vowel "a" Collected Via Mobile Phone From Individuals Diagnosed With Chronic Obstructive Pulmonary Disease and Health Control Groups

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 48 (actual)
• Sponsor: Blekinge Institute of Technology · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The Study aims to identify the changes in voice caused by Chronic Obstructive Pulmonary Disease (COPD) statistically for identifying the potential digital voice biomarkers.

Detailed description

1058 voice recordings collected via mobile phones over time in form of the Swedish utterance of vowel "a" will be analysed using vowel quadrilateral space and the Mann-Whitney U test. The significance threshold p-value will be set to 0.05, and vocal features consisting of 101 base line acoustic features and MFCC features will be analysed between the COPD and HC groups. The most significant features that remain under the significance threshold will be reported.

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
OTHER	Chronic Obstructive Pulmonary Disease (COPD)	The base line acoustic and mel frequency ceprtum coefficients will be analysed statistically between COPD voices and healthy control groups to highlight the correlation between COPD and its effects on voice production.

Timeline

• Start date: 2024-10-28
• Primary completion: 2025-02-28
• Completion: 2025-03-30
• First posted: 2024-11-26
• Last updated: 2024-11-26

Locations

1 site across 1 country: Sweden