NCT06700629

Distal Hypospadias Repair Outcome

Preoperative Predictors of Distal Hypospadias Repair Outcome

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Armia Ezzat Thabet Azer · Academic / Other
• Sex: Male
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

Aim is : To define the preoperative parameters that may influence the results of distal hypospadias repair

Detailed description

Hypospadias is a congenital deformity where the opening of the urethra (the meatus) is sited on the underside (ventral) part of the penis, anywhere from the glans to the perineum. It occurs in 1 in 250 live male births. it is often associated with "hooded" foreskin and chordee (ventral curvature of the penis shaft). Hypospadias can be classified according to the anatomical location of meatus: Distal-anterior hypospadias (located on the glans or distal shaft of the penis and the most common type of hypospadias) Intermediate-middle (penile). Proximal-posterior (penoscrotal, scrotal, perineal). Diagnosis includes a description of the local findings: Position, shape and width of the orifice Presence of atretic urethra and division of corpus spongiosum Appearance of the preputial hood and scrotum Size of the penis Curvature of the penis on erection. Aim of hypospadias surgery :(2) Is to correct penile curvature,to form neo-urethera of an adequate size, to bring the neomeatus to the tip of glans, and offer satisfactory cosmetic results. The ideal age at surgery for primary hypospadias repair is usually 6-18 months. The complication rate is about 10% in distal hypospadias repair. Complications include: 1. uretherocutaneous fistula. 2. meatal stenosis. 3. urethral stricture. 4. Urethral diverticulum. After hypospadias repairs, long-term follow-up is necessary, up to adolescence, to detect urethral stricture, voiding dysfunction and recurrent penile curvature.

Conditions

• Distal Penile Hypospadias (Disorder)

Interventions

Type	Name	Description
PROCEDURE	Distal Penile Hypospadias (Disorder)	Three operations which are Tubularized incised plate urethroplasty (TIP), Mathieu and meatal advancement and glanuplasty (MAGPI). A three experienced operators with number of operations done by each one more than one hundred operation in the last year. The operators will be fixed for each surgical technique as follows: 1. Doctor (A) for Matheiu. ( 35 operations) 2. Doctor (M) for MAGPI. ( 35 operations) 3. Doctor (S) for TIP ( 35 operations). Tubularized incised plate urethroplasty:(3,6) Indication: for distal penile hypospadias with or without penile curvature with any width of the uretheral plate and also for any type of distal hypospadias associated with curvature. Key steps for this operation are as follows: Glans retraction using stay suture 4-0 or 5-0 silk. Uretheral catheter pass through hypospadic meatus to bladder. Parallel longitudenal incision is done 1-2mm proximal to hypospadic meatus. A circumferential incision is made 2-3 mm below coronal sulcus dorsally

Timeline

• Start date: 2025-01-01
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2024-11-22
• Last updated: 2024-11-22

Locations

2 sites across 1 country: Egypt