NCT06697119

Efficacy and Safety of Fecal Microbiota Transplantation in Patients with Irritable Bowel Syndrome

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to assess the efficacy and safety of fecal microbiota transplantation (FMT) for patients with irritable bowel syndrome (IBS). The main objectives of the study are: To determine if FMT can significantly reduce IBS symptoms and improve patients' quality of life. To evaluate any potential adverse effects associated with FMT in IBS patients. Researchers will compare outcomes in patients receiving FMT with a standard care protocol to gauge the effectiveness of FMT in alleviating IBS symptoms. Participants will: Receive FMT via endoscopic methods as per the study protocol. Attend scheduled clinic visits for assessments and symptom tracking over a 48-week period, with optional long-term follow-up for up to 3 years. Complete regular questionnaires and microbiota assessments to monitor symptoms and gut health changes over time.

Conditions

• Irritable Bowel Disease

Interventions

Type	Name	Description
OTHER	Fecal Microbial Transplantation	Fecal suspension is delivered to duodenal 3rd portion via esophagogastroduodenoscopy

Timeline

• Start date: 2023-03-09
• Primary completion: 2024-07-03
• Completion: 2027-04-25
• First posted: 2024-11-20
• Last updated: 2024-11-20

Locations

1 site across 1 country: South Korea