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RecruitingNCT06696638

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

Physiological Effects of Lung Impedance Tomography-guided and Plat Pressure-guided Phigh During Airway Pressure Release Ventilation in Patients With Acute Respiratory Distress Syndrome

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
26 (estimated)
Sponsor
XiaoJing Zou,MD · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.

Conditions

Interventions

TypeNameDescription
DEVICEEIT-guided Phigh settings during APRVThe Phigh level selected for the patients in the Intervention group was the intercept point of cumulated collapse and overdistension percentage curves, providing the best compromise between collapsed and overdistended lung.

Timeline

Start date
2025-01-01
Primary completion
2026-12-31
Completion
2026-12-31
First posted
2024-11-20
Last updated
2025-01-06

Locations

1 site across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT06696638. Inclusion in this directory is not an endorsement.

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With AR (NCT06696638) · Clinical Trials Directory