NCT06695546

Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.

Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children. VExUS-Mod

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 67 (actual)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact. This score was initially evaluated and validated on an adult population. ) In children, there is only one study looking at the use and applicability of this VExUS score, highlighting its feasibility in a paediatric population, as well as a possible correlation between elevated central venous pressure and altered renal Doppler (one of the score's components).

Conditions

• Blood Volume Expansion

Interventions

Type	Name	Description
OTHER	VExUS evaluation ultrasound	VExUS evaluation by ultrasound will be performed before the filling/bleeding/cleaning procedure, and again after the procedure: * Inferior vena cava measurement in Time-Motion (TM) mode, 1-2 cm from the right atrial orifice. * Hepatic venous Doppler measurement in pulsed Doppler mode. * Renal vein Doppler measurement in pulsed Doppler mode. Each measurement is performed three times consecutively (to average the results), then the ultrasound measurements are compiled into a score according to the degree of doppler severity.

Timeline

• Start date: 2024-12-10
• Primary completion: 2025-06-06
• Completion: 2025-06-06
• First posted: 2024-11-19
• Last updated: 2026-01-14

Locations

1 site across 1 country: France