NCT06691568

Effectiveness of an Air Purifier on Asthmatic and Cat-allergic Subjects in the ALYATEC Environmental Exposure Chamber

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Dyson Technology Ltd · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate the efficacy of air purifiers in reducing allergy symptoms in patients with a cat allergy. The main question it aims to answer is: If there is a reduction of early asthmatic response (EAR) compared to placebo. Participants were asked to remain in an exposure chamber for 2 hours while their symptoms were monitored.

Detailed description

For this protocol, 30 patients with cat allergies were exposed to 80ng/m3 of Fel d 1 allergen in the ALYATEC Environmental Exposure Chamber (EEC). The active group of 15 had Dyson BP06 air purifiers running at speed 2, while the placebo group had the purifiers on, but not circulating air (speed 0). Participants were monitored for the primary objective of reduction of EAR, alongside other secondary objectives: 1. To evaluate the efficacy of air purifier on time to induce EAR during a 2-hour cat allergen exposure in ALYATEC EEC compared to placebo 2. To evaluate the efficacy of air purifier on allergic rhino-conjunctivitis symptoms during a 2-hour cat allergen exposure in ALYATEC EEC compared to a placebo 3. To evaluate the efficacy of air purifier on bronchial response severity during a 2-hour cat allergen exposure in ALYATEC EEC compared to placebo. 4. To evaluate the rescue treatments used after 2-hour cat allergen exposure with the air purifier compared to placebo 5. To evaluate the efficacy of air purifier on allergic rhinitis symptoms during a 2-hour cat allergen exposure in ALYATEC EEC compared to a placebo

Conditions

• Cat Allergy

Interventions

Type	Name	Description
DEVICE	Air purifier	Purifiers were turned on for the active group and off for the placebo

Timeline

• Start date: 2023-01-20
• Primary completion: 2023-10-26
• Completion: 2023-10-26
• First posted: 2024-11-15
• Last updated: 2024-11-15

Locations

1 site across 1 country: France