NCT06690307

Oxycodone Versus Sufentanil in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy

The Efficacy and Safety of Oxycodone in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Affiliated Hospital of Nantong University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to evaluate the efficacy and safety of hydrocodone in patient-controlled intravenous analgesia (PCIA) during gynecological laparoscopy, thus to explore suitable PCIA scheme to optimize postoperative pain management for patients undergoing gynecological laparoscopic surgeries.

Detailed description

The controlled group will receive sulfentanil for PCIA, and the test group will receive hydrocodone for PCIA. NRS scores at 1, 6, 24 and 48 hours post-surgery will be recorded. The usage of rescue analgesics and adverse events will also be recorded.

Conditions

• Laparoscopic Hysterectomy

Interventions

Type	Name	Description
PROCEDURE	patient controlled intravenous analgesia(PCIA)	Patients will receive sulfentanil for PCIA.
PROCEDURE	patient controlled intravenous analgesia(PCIA)	Patients will receive oxycodone for PCIA.

Timeline

• Start date: 2024-12-03
• Primary completion: 2025-12-31
• Completion: 2026-07-31
• First posted: 2024-11-15
• Last updated: 2024-12-04

Locations

1 site across 1 country: China