NCT06684951

Effects of Intrauterine Flushing With Human Chorionic Gonadotropin on ICSI Outcome

Study the Effects of Intrauterine Flushing With Low Dose Human Chorionic Gonadotropin on Ultrasound Parameter and Immunological Marker of Endometrial Receptivity of Infertile Female Undergoing ICSI Cycle

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Omayma Ismail Khalaf · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

a number of infertile women who were prepared for ICSI and immediately post ova pick up intrauterine flushing with human chorionic gonadotropin was done to study the effect of this drug on ICSI outcome and ultrasound parameter.

Detailed description

Ninety infertile women included. Written informed consent was obtained before being included in the study. Three groups of patients according to type of intervention. Assessment of plasma hormone level was done for all. The quantification of serum TNF and IL-10 levels was conducted through the application of the enzyme-linked immunosorbent assay (ELISA) methodology at a privately-owned laboratory.

Conditions

• Female Infertility

Interventions

Type	Name	Description
DRUG	hCG	observe hCG effect on endometrial receptivity

Timeline

• Start date: 2022-10-23
• Primary completion: 2024-01-23
• Completion: 2024-04-30
• First posted: 2024-11-12
• Last updated: 2025-09-19
• Results posted: 2025-04-27

Locations

1 site across 1 country: Iraq

Regulatory

• FDA-regulated drug study