NCT06684080

The Effectiveness of a Care Bundle to Prevent Postpartum Hemorrhage After Cesarean Delivery

A Cluster Randomized Trial on the Effectiveness of a Care Bundle to Prevent Postpartum Hemorrhage After Cesarean Delivery (Re-Team)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 52,000 (estimated)
• Sponsor: Dunjin Chen · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Delays in the detection or inconsistent use of effective interventions of postpartum hemorrhage can result in complications or death. We designed a cluster-randomized trial to assess a multi-component strategy for the detection and treatment of postpartum hemorrhage after cesarean delivery.

Conditions

• Cesarean Delivery

Interventions

Type	Name	Description
OTHER	A care bundle	1. Risk evaluation for PPH and Reserve plan; 2. Assess blood loss using Estimated Blood Loss Form and amnion fluid collection drape; 3. Satisfy any of the following conditions: i. If the estimated blood loss reaches 500ml but is less than 1000ml, and any of the following abnormal indicators are present; ii. If the estimated blood loss reaches 1000ml, no other indicators need to be considered: 1） Lack of uterine contractions 2） Persistent bleeding 3）Shock index (heart rate/systolic blood pressure) was greater than 0.9 Initiate the following protocols①, ②, ③, ④ * Maintain uterus tone (Administration of Oxytocin and second-line medications to promote uterine contraction) * Intravenous infusion ③ Administered tranexamic acid ④ Multi-methods and Multi-disciplinary

Timeline

• Start date: 2025-01-01
• Primary completion: 2026-12-31
• Completion: 2027-06-30
• First posted: 2024-11-12
• Last updated: 2025-01-01