NCT06683014

MDMA in Borderline Personality Disorder

The Effects of MDMA (3,4-methylenedioxymethamphetamine) in Social Cognition in Borderline Personality Disorder

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the effects of MDMA (3,4-methylenedioxymethamphetamine) on social cognition in adults with Borderline Personality Disorder.

Conditions

• Borderline Personality Disorder

Interventions

Type	Name	Description
DRUG	MDMA	Participants will receive one dose of open-label 3,4-methylenedioxymethamphetamine (MDMA).

Timeline

• Start date: 2025-09-05
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2024-11-12
• Last updated: 2026-01-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study