NCT06682078

Disorders of Sexual Development and Gonadal Tumor Risk

DEV-GEN-RiTuGo - Assessment of Individual Gonadal Tumor Risk in Patients With Disorders of Sexual Developpment According to the Etiology.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 80 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Disorders of Sexual Development are rare and represent a spectrum of heterogeneous pathologies. The risk of developing a malignant gonadal germ cell tumor (MGCT) exists and varies according to the etiology. The indication for prophylactic gonadectomy must be modulated and discussed for all patients. It is essential to assess each patient's individual risk. The aim of our study is to assess gonadal tumor risk in patients with Disorders of Sexual Development according to etiology The primary objective is to evaluate tumor risk and the indication for gonadectomy in cases of Disorders of Sexual Development according to etiology. The secondary objectives are to evaluate the timing of gonadectomy, to monitor changes in practice over time, and to assess the contribution of imaging and/or biological tests to tumor detection.

Conditions

• Disorders of Sexual Development

Interventions

Type	Name	Description
OTHER	Not applicable . Non-interventional retrospective study, only on datas.	Not applicable . Non-interventional retrospective study, only on datas.

Timeline

• Start date: 2023-09-01
• Primary completion: 2023-12-01
• Completion: 2024-06-01
• First posted: 2024-11-12
• Last updated: 2025-04-13

Locations

1 site across 1 country: France