NCT06681818

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 125 (estimated)
• Sponsor: Englewood Hospital and Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship to the extent of hepatic resection (2) to assess the production of CO in patients following liver resection and correlate these findings to the rate of liver regeneration and liver function.

Conditions

• Liver Cancer Adult
• Liver Regeneration

Interventions

Type	Name	Description
OTHER	carbon monoxide measurement via smokerlyzer	participants in this study will provide breath samples for carbon monoxide measurements pre and post liver resection

Timeline

• Start date: 2025-11-21
• Primary completion: 2039-01-01
• Completion: 2039-01-01
• First posted: 2024-11-08
• Last updated: 2025-07-23

Locations

1 site across 1 country: United States