NCT06680895

FeNO Observation Study in ICU Patients With ARS

An Observational Study of Fractional Exhaled Nitric Oxide Concentration in Patients With Advanced Respiratory Support

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: —

Summary

1. Main Objective: To compare the concentration of exhaled nitric oxide in patients with different severity of respiratory failure in ICU. 2. Secondary Purpose: 1. To observe the change of nitric oxide concentration in exhaled breath of patients with mechanical ventilation over time; 2. The relationship and differences between pulmonary ventilation blood flow levels in patients with different exhaled NO concentrations; 3. Reactivity of patients with different exhaled NO concentrations to inhaled nitric oxide therapy and the relationship between them.

Conditions

• Compare the Concentration of Exhaled Nitric Oxide in Patients With Different Severity of RF

Interventions

Type	Name	Description
OTHER	FeNO Observation	FeNO was observed and measured among patients with advanced respiratory support

Timeline

• Start date: 2024-07-01
• Primary completion: 2025-09-30
• Completion: 2025-12-31
• First posted: 2024-11-08
• Last updated: 2024-11-08

Locations

1 site across 1 country: China