NCT06680882

The Effect of Non-invasive Auricular Acupoint Stimulation on Slow Transmission Constipation

The Second Hospital Affiliated Anhui University of Chinese Medicine

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Objective To examine the therapeutic effect and safety of non-invasive auricular acupoint stimulation application on patients with slow transmission constipation. Methods In a randomized clinical trial, 60 patients diagnosed with slow transit constipation (STC), ranging in age from 40 to 75 years, were allocated into two distinct cohorts: a study group and a control group. The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride, while the control group, also consisting of 30 patients, was administered prucapride as a monotherapy. To assess the efficacy of the interventions, various parameters were monitored, including serum levels of Neuropeptide Y (NPY), nitric oxide (NO), fecal water content, and gastrointestinal (GI) transit. The comparative therapeutic outcomes were determined by calculating symptom scores.

Conditions

• Slow Transmission Constipation

Interventions

Type	Name	Description
OTHER	Auricular Acupoint Stimulation +prucapride	The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride
DRUG	prucapride	was administered prucapride as a monotherapy

Timeline

• Start date: 2024-11-07
• Primary completion: 2024-11-07
• Completion: 2025-11-01
• First posted: 2024-11-08
• Last updated: 2024-11-08