NCT06680336

Cognitive Recovery After Post Stroke Delirium (RECOVER)

Cognitive Recovery After Post Stroke Delirium [RECOVER] a Longitudinal Pilot Proof of Concept Study in Stroke Patients With/without Delirium

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

RECOVER is a Proof-of-Concept study on cognitive functioning following a longitudinal design with three measurements (during the acute- and post-acute phases of a stroke and a 3-month follow-up) and two equally-sized stroke patient groups: a post-stroke delirium(PSD), and a non-PSD group (control group). Cognitive functioning will be assessed using a multi-component neuropsychological assessment and tasked-based functional MRI (introducing a modified working memory task).

Conditions

• Post Stroke Delirium
• Cognitive Functioning After Stroke

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Mulit-componant neuropsychological assessment	Multi-component cognitive assessment including following domains: attention \& information speed, executive functioning, verbal memory, language, visuospatial-construction and orientation.
DIAGNOSTIC_TEST	Multimodal MRI	Structural MRI (e.g., MPRAGE, DTI) and functional MRI (introducing a modified working memory task for stroke patients)

Timeline

• Start date: 2023-12-01
• Primary completion: 2025-08-01
• Completion: 2025-11-01
• First posted: 2024-11-08
• Last updated: 2024-11-08

Locations

1 site across 1 country: Germany