NCT06679569

Deep Neuromuscular Blockade on Postoperative Pain

Effect of Deep Neuromuscular Blockade on Postoperative Pain in Pediatric Patients Undergoing Laparoscopic Surgery: a Prospective Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 106 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 2 Months – 7 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate the impact of varying degrees of neuromuscular blockade on postoperative pain in pediatric patients aged over 2 months to under 7 years undergoing laparoscopic surgery under general anesthesia.

Conditions

• Neuromuscular Blockade

Interventions

Type	Name	Description
DRUG	rocuronium 0.2 mg/kg/hr continuous infusion	To maintain Train-of-four count 1 to 3 during surgery: Administration of continuous infusion of rocuronium at a rate of 0.2 mg/kg/hr to achieve and sustain moderate neuromuscular blockade.
DRUG	rocuronium 0.6 mg/kg/hr continuous infusion	To maintain Train-of-four count 0 during surgery: Administration of continuous infusion of rocuronium at a rate of 0.6 mg/kg/hr to achieve and sustain deep neuromuscular blockade.

Timeline

• Start date: 2024-11-06
• Primary completion: 2026-11-06
• Completion: 2026-11-07
• First posted: 2024-11-07
• Last updated: 2025-05-13

Locations

1 site across 1 country: South Korea