NCT06678438

Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,716 (estimated)
• Sponsor: Nordsjaellands Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the project is to evaluate the beneficial and harmful effects of an ultrasound-guided brachial plexus nerve block for patients with a distal radius (wrist) fracture in the need of realignment of fractured bone endings without cutting the skin (closed reduction), in comparison to a haematoma block, which is standard care in Denmark. Every participant will receive one of the following types of anaesthesia for the realignment of the wrist fracture: 1. A nerve block of the arm (plexus brachialis block) 2. A haematoma block, which is the current standard anaesthesia in the emergency departments.

Conditions

• Distal Radius Fractures
• Fracture Dislocation
• Fracture Dislocation of Upper Limb Joint
• Colles' Fracture
• Closed Reduction of Fracture and Application of Plaster Cast

Interventions

Type	Name	Description
PROCEDURE	Ultrasound-guided brachial plexus block	The block will be performed as either a lateral infraclavicular brachial plexus block or an axillary brachial plexus block
PROCEDURE	Haematoma Block	Participants will receive no peripheral nerve block and receive a haematoma block, with or without supplemental sedation and/or systemic analgesia for the closed reduction according to local guidelines and clinical practices

Timeline

• Start date: 2024-12-10
• Primary completion: 2026-11-01
• Completion: 2027-04-01
• First posted: 2024-11-07
• Last updated: 2025-06-17

Locations

1 site across 1 country: Denmark