NCT06673901

Biomechanical Changes in Females with Poly Cystic Ovarian Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 95 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: 25 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder that causes an inversion of the normal luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratio. Females with PCOS also experience chronic inflammation. This hormonal imbalance and persistent inflammation can reduce muscle strength and mass. Consequently, this may affect the lumbopelvic muscles, potentially leading to postural abnormalities and spinopelvic misalignment.

Detailed description

1.1. Study design This was an observational case-control study. Participants This study enrolled 95 females (52 PCOS, 43 Controls) who agreed to participate in this research. They signed an informed consent after explaining the existence, purpose, and advantages of the study, notifying them of their right to refuse or withdraw at any time. Patients were excluded from the study if they suffered from skeletal deformities (one case), had previous spinal surgeries (one case), had leg length discrepancy (one case) and two cases received hormone replacement therapy

Conditions

• Poly Cystic Ovarian Syndrome
• Polycystic Ovary Syndrome (PCOS)

Interventions

Type	Name	Description
DEVICE	Measurments	Each angle was measured three times, and the mean was calculated to represent the data used for statistical analysis. The assessment position for all measurements was relaxed, comfortable standing position and wearing loose clothing, bare feet, and one foot apart between two feet on a level floor in the same room of the same building, at the same time of day. There was a fixed point in the wall, and the woman was instructed to look at it during the assessment; this point adjusts at the level of her eyes. No specific instructions were provided to the females regarding posture so that measurements during a normal standing position. Data was recorded in a data-collecting sheet.

Timeline

• Start date: 2023-04-03
• Primary completion: 2024-08-03
• Completion: 2024-09-03
• First posted: 2024-11-05
• Last updated: 2024-11-05

Locations

1 site across 1 country: Egypt