NCT06673121

Respiratory Disease Cohort Studies of Chinese Medicine for Pulmonary Nodule

Respiratory Disease Cohort Studies of Chinese Medicine for Pulmonary Nodule （RESEARCH-PN）

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: Third Affiliated Hospital of Henan University of Traditional Chinese Medicine · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is a prospective multicenter cohort study that primarily evaluates the impact of traditional Chinese medicine treatment on pulmonary nodules

Detailed description

This study is a multicenter, prospective cohort study that will recruit at least 2244 individuals with chest HRCT findings of pulmonary nodules and recommended follow-up by MDT from four research centers. According to whether patients with pulmonary nodules are treated with traditional Chinese medicine, they are divided into a traditional Chinese medicine cohort and a non-traditional Chinese medicine cohort , and are followed up for at least 2 years. The main outcome measures were pulmonary nodule growth (enlargement or new onset) and nodule regression (reduction or disappearance). To evaluate the efficacy of traditional Chinese medicine treatment for patients with pulmonary nodules, secondary outcome measures include nodule volume, average nodule density, doubling time of volume, internal and external signs of nodules, anxiety self-assessment scale, depression self-assessment scale and SF-36 scale.

Conditions

• Pulmonary Nodule
• Cohort Study
• Traditional Chinese Medicine

Interventions

Type	Name	Description
DRUG	Traditional Chinese Medicine	Received treatment with traditional Chinese medicine

Timeline

• Start date: 2024-01-03
• Primary completion: 2028-12-30
• Completion: 2029-12-30
• First posted: 2024-11-04
• Last updated: 2024-11-04

Locations

1 site across 1 country: China