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Not Yet RecruitingNCT06672263

A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia

Phase I Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia

Status
Not Yet Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
120 (estimated)
Sponsor
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Phase I clinical trial to explore the safety, tolerability, and initial efficacy of TQB3911 tablets in BCR::ABL fusion gene positive leukemia.

Conditions

Interventions

TypeNameDescription
DRUGTQB3911 tabletsTQB3911 is a small molecule BCR::ABL1 allosteric inhibitor. By occupying the myristyl binding site, TQB3911 recovers the inhibition of BCR::ABL1 fusion protein kinase activity, and ultimately inhibits the proliferation of tumor cells.

Timeline

Start date
2024-11-01
Primary completion
2026-09-01
Completion
2026-12-01
First posted
2024-11-04
Last updated
2024-11-04

Locations

5 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06672263. Inclusion in this directory is not an endorsement.

A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positi (NCT06672263) · Clinical Trials Directory