NCT06670690

Comparison Between Atenolol,Propnalol and Ivabradine

Comparison Between Atenolol , Propnalol and Ivabradine as a Premedication for Bloodless Field Anesthesia in Lumbar Spine Surgery ,a Prospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Menoufia University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.

Detailed description

This study will investigate the effect of atenolol, propranolol, and ivabradine as oral premedication in adult patients undergoing LUMBAR SPINE SURGERY to achieve bloodless field anesthesia. AIM OF THE WORK * The primary aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery. * The secondary aims are to assess field visibility and measure the amount of blood loss in patients, and surgeon satisfaction and also to asses if there are any associated undesirable side effects of atenolol, propranolol, or Ivabradine will appear.

Conditions

• Intraoperative Bleeding

Interventions

Type	Name	Description
DRUG	Atenolol 50 MG	patients will be premedicated with atenolol (50mg)
DRUG	Propranolol Pill	patients will be premedicated with propranolol (10mg)
DRUG	Ivabradine	patients will be premedicated with Ivabradine (5mg)

Timeline

• Start date: 2023-09-01
• Primary completion: 2023-09-01
• Completion: 2023-10-01
• First posted: 2024-11-01
• Last updated: 2024-11-01

Locations

1 site across 1 country: Egypt