NCT06670391

A Retrospective Study in Patients With Liver Injury After the Use of Novel Antineoplastic Agents

A Retrospective, Real-world, Electronic Medical Record-based Study on Patients With Liver Injury After the Administration of Novel Antineoplastic Agents

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Drug Induced Liver Disease Study Group · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an open-enrollment, retrospective, observational study without interventions. Its primary objective is to understand 1) incidence of liver injury among all the hospitalized patient from participating centers after the administration of immune checkpoint inhibitors or molecularly targeted agents; 2) epidemiologic and clinical characteristics of liver injury, including suspected medications, clinical types, histological characteristics, severity, treatment and outcomes.

Conditions

• Liver Injury
• Liver Injury, Drug-Induced

Timeline

• Start date: 2023-05-01
• Primary completion: 2025-04-30
• Completion: 2025-12-31
• First posted: 2024-11-01
• Last updated: 2025-05-04

Locations

1 site across 1 country: China