NCT06670339

Effect of Pre-cooling on Whole-body Heat Loss During Exercise-heat Stress

Effect of Pre-cooling the Body on Whole-body Heat Exchange in Young Males During Exercise in the Heat

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of Ottawa · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

Endurance exercise performance declines in hot environments as core body temperature increases. To enhance performance, body pre-cooling strategies, such as cold-water immersion have been employed to lower resting core temperature thereby increasing the body's heat storage capacity. In turn, the increase in body core temperature associated with exercise in the heat is blunted, allowing the individual to exercise at higher intensity and or for a longer period of time. However, the mechanisms by which pre-cooling impacts heat exchange during exercise remain unclear. While existing research has focused on the performance benefits of pre-cooling the body, relatively little is known about the impacts of pre-cooling on whole-body heat exchange during an exercise-heat stress. Investigators will therefore evaluate whole-body heat exchange (dry ± evaporative heat loss as assessed using a direct air calorimeter) during a prolonged (1-hour) moderate-intensity cycling bout in the heat (wet-bulb globe temperature of 29°C; equivalent to 37.5°C, 35% relative humidity) performed with and without pre-cooling by cool-water (\~17°C) immersion.

Conditions

• Thermoregulation
• Cold Exposure
• Heat Stress
• Exercise

Interventions

Type	Name	Description
OTHER	No Cooling	Participants will not be pre-cooled prior to completing a 60-minute moderate-intensity exercise bout in the heat.
OTHER	Pre-Cooling	Participants will be immersed in cold (\~17°C) water to elicit a decrease in rectal temperature by 0.5°C from baseline values prior to completing a 60-min moderate-intensity exercise bout in the heat.

Timeline

• Start date: 2024-10-24
• Primary completion: 2025-02-27
• Completion: 2025-02-27
• First posted: 2024-11-01
• Last updated: 2025-06-17

Locations

1 site across 1 country: Canada