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Not Yet RecruitingNCT06669143

Zanubrutinib-based Maintenance Therapy of Newly Diagnosed DLBCL With Initial Remission

The Efficacy and Safety of Zanubutinib-based for Post-remission Maintenance in Patients With Diffuse Large B-cell Lymphoma Who Are Intolerant to Intense First-line Chemotherapy

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
19 (estimated)
Sponsor
Ruijin Hospital · Academic / Other
Sex
All
Age
70 Years
Healthy volunteers
Not accepted

Summary

This single-arm, prospective clinical study will evaluate the efficacy and safety of Zanubrutinib-based maintenance therapy for post-remission in newly diagnosed DLBCL who are intolerant to first-line intensive chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGZanubrutinib160 mg bid, po, day 1-21, a maximum of 2 years.
DRUGLenalidomide25 mg qd, po, day 1-10, a maximum of 2 years.

Timeline

Start date
2024-11-01
Primary completion
2026-11-01
Completion
2027-12-01
First posted
2024-11-01
Last updated
2024-11-01

Source: ClinicalTrials.gov record NCT06669143. Inclusion in this directory is not an endorsement.

Zanubrutinib-based Maintenance Therapy of Newly Diagnosed DLBCL With Initial Remission (NCT06669143) · Clinical Trials Directory