NCT06661746

Efficient Postoperative Pain Management With Multimodal IV

Multimodal Intravenous Analgesia Using Half-dose of Ketamine, Lidocaine and Magnesium Sulfate Provides Efficient Postoperative Analgesia for Patients Undergoing Major Abdominal Surgery: Randomized, Case-controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects. Epidural analgesia, though a viable option, carries its risks and complications. Recent research indicates that combining intravenous lidocaine and ketamine can significantly alleviate postoperative pain and decrease the reliance on opioids within the initial 24 hours following surgery. This approach offers a promising alternative with minimal additional adverse effects, suggesting a potential shift in pain management practices.

Conditions

• Post Operative Pain

Interventions

Type	Name	Description
DRUG	Multimodal IV analgesia	Multimodal IV analgesia of lidocaine, ketamine and MS
DRUG	epidural analgesia	Opioid-based and epidural analgesia

Timeline

• Start date: 2024-07-15
• Primary completion: 2024-10-30
• Completion: 2024-11-15
• First posted: 2024-10-28
• Last updated: 2024-12-24

Locations

1 site across 1 country: Egypt