NCT06661447

Bone Augmentation Techniques in the Mandible Posterior Region

Comparison of Bone Augmentation Techniques in the Mandibular Posterior Region: A Randomized Clinical Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (estimated)
• Sponsor: Universidad de Especialidades Espiritu Santo · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement. Seventy-eight adults will be randomly assigned to receive one of three "cortical shell" techniques using either the patient's own bone (autogenous) or prefabricated bone plates from animal (xenogeneic) or human donors (allogeneic). In all groups, the space inside the shell will be filled with a mixture of small bone chips and bone substitute material. The main outcome is the increase in jawbone width measured on 3D cone-beam CT scans at 6 months after surgery. Additional scans and clinical assessments up to 12 months will evaluate healing, bone stability, and postoperative recovery.

Conditions

• Bone Substitutes
• Alveolar Bone Grafting

Interventions

Type	Name	Description
PROCEDURE	Cortical Shell Bone Grafting	Surgical reconstruction of atrophic posterior mandibular ridges using thin cortical plates fixed with titanium microscrews to form a biologic shell. The inner space is filled with a 1:1 mixture of autogenous bone chips and biomaterial. Depending on the study group, the cortical plates are autogenous (from the mandibular ramus), xenogeneic (bovine origin), or allogeneic (human donor).

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-11-01
• Completion: 2027-04-01
• First posted: 2024-10-28
• Last updated: 2026-02-20

Locations

1 site across 1 country: Ecuador