NCT06660004

Creatine HCl and Creatine Ethyl Ester Supplementation in Perimenopausal and Menopausal Women

The Effects of 8-Week Creatine HCl and Creatine Ethyl Ester Supplementation on Cognitive Performance, Multidimensional Fatigue, Brain Metabolism, and Biochemical Indices in Perimenopausal and Menopausal Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: University of Novi Sad, Faculty of Sport and Physical Education · Academic / Other
• Sex: Female
• Age: 40 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of of dietary supplementation with creatine HCl and creatine ethyl ester supplementation on cognitive performance, multidimensional fatigue, brain metabolism, and biochemical indices in perimenopausal and menopausal women

Conditions

• Menopausal
• Perimenopause

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dietary Supplement: Experimental 1 Creatine HCl	Creatine hcl
DIETARY_SUPPLEMENT	Dietary Supplement: Experimental 2 Creatine HCl	Creatine hcl
DIETARY_SUPPLEMENT	Dietary Supplement: Experimental 3 Creatine Ethyl ester	Creatine ethyl ester
DIETARY_SUPPLEMENT	Dietary Supplement: Experimental 4 Placebo	Placebo

Timeline

• Start date: 2024-11-15
• Primary completion: 2025-05-15
• Completion: 2025-05-31
• First posted: 2024-10-26
• Last updated: 2025-12-16

Locations

1 site across 1 country: Serbia