NCT06659991

JIT: Effect of Pain on DT in TMD

JIT: Effects of Pain on Laboratory Drinking Topography and Daily Drinking in People With Chronic Temporomandibular Disorder (TMD) Pain

• Status: Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.

Conditions

• Temporomandibular Disorder (TMD)

Interventions

Type	Name	Description
DRUG	alcohol condition	Ethanol
OTHER	control condition	sparkling water

Timeline

• Start date: 2025-05-14
• Primary completion: 2029-09-07
• Completion: 2029-09-07
• First posted: 2024-10-26
• Last updated: 2026-02-12

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study