NCT06657547

Urinary Concentration After Salmeterol

Urinary Concentration After Salmeterol in Well-trained Men and Females

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the project is to investigate urine concentration after inhalation of salmeterol. This will be examined following acute physical activity under both normal conditions and heated conditions.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Normal conditions	Participants are administered salmeterol, after which they perform various performance tests in normal conditions. Following the administration of salmeterol, urine samples are collected over the next 24 hours at intervals of 0.5, 1, 2, 4, 8, and 24 hours after administration.
OTHER	Heated conditions	Participants are administered salmeterol, after which they perform various performance tests in heated conditions. Following the administration of salmeterol, urine samples are collected over the next 24 hours at intervals of 0.5, 1, 2, 4, 8, and 24 hours after administration.
DRUG	Salmeterol inhalation and urine samples	After the experimental day under normal conditions, all participants are administered 200 µg of salmeterol daily (8 puffs from the MDI device) during a 6-day intervention period. Two hours after inhalation, the participants collect spot urine samples at home

Timeline

• Start date: 2024-10-31
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2024-10-24
• Last updated: 2025-04-09

Locations

1 site across 1 country: Denmark