NCT06654063

Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D Daily Supplements on Active Periodontal Therapy With Stage II Grade B Periodontitis Patients

Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D Daily Supplements on Active Periodontal Therapy With Stage II Grade B Periodontitis Patients: A Randomized Controlled Clinical Trial.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D daily Supplements on Active Periodontal Therapy with Stage II Grade B Periodontitis Patients: A Randomized controlled clinical trial.

Detailed description

This randomized clinical trial evaluates the effect of Omega- 3 versus Vitamin D regarding Clinical evaluation 1. Clinical attachment loss (CAL) 2. Plaque index (PI) 3. Gingival index (GI)

Conditions

• Vitamin D Deficiency

Interventions

Type	Name	Description
PROCEDURE	non-surgical periodontal therapy (SRP)	* The CAL PPD and mSBI will be measured for each patient and will be recorded at baseline and 6 weeks * all patients will receive supragingival and sub-gingival plaque and calculus debridement (SRP) with an ultrasonic scaler (Various 350; NSK, Japan) and a manual universal curette (Gracey; Hu-Friday, Chicago, USA) where, conventional scaling and root planning (SRP) to the bottom of the pocket of 4 mm or more * Subgingival saline irrigation will be performed adjunctively to Sub-gingival curettage.
DIETARY_SUPPLEMENT	non-surgical periodontal therapy (SRP)+ Omega-3	* The CAL PPD and mSBI will be measured for each patient and will be recorded at baseline and 6 weeks * all patients will receive supragingival and sub-gingival plaque and calculus debridement (SRP) with an ultrasonic scaler (Various 350; NSK, Japan) and a manual universal curette (Gracey; Hu-Friday, Chicago, USA) * Subgingival saline irrigation will be performed adjunctively to Sub-gingival curettage. * Patients will start taking Omega-3 supplements on the day of SRP procedure.
DIETARY_SUPPLEMENT	non-surgical periodontal therapy (SRP)+ Vitamin D	* The CAL PPD and mSBI will be measured for each patient and will be recorded at baseline and 6 weeks * all patients will receive supragingival and sub-gingival plaque and calculus debridement (SRP) with an ultrasonic scaler (Various 350; NSK, Japan) and a manual universal curette (Gracey; Hu-Friday, Chicago, USA) where, conventional scaling and root planning (SRP) to the bottom of the pocket of 4 mm or more * Subgingival saline irrigation will be performed adjunctively to Sub-gingival curettage. * Serum vitamin D levels will be assessed at baseline and 6 weeks after intervention in all groups.

Timeline

• Start date: 2025-04-01
• Primary completion: 2025-06-01
• Completion: 2025-12-01
• First posted: 2024-10-23
• Last updated: 2025-12-12

Locations

1 site across 1 country: Egypt