NCT06649071

Clinical Classification and Imaging Markers in Patients of Obesity

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This is an observational study to explore the etiology and clinical classification in patients with obesity and to achieve personalized treatment.

Detailed description

In this project, individuals with obesity and control individuals were recruited and followed up every year. Clinical neuropsychological scores, olfactory function tests, and functional magnetic resonance imaging (fmri) were performed to describe the brain function characteristics under different odor stimulation in fasting and after eating, and to explore the pathogenesis and clinical classification of obese patients. The correlation analysis between imaging analysis values and clinical laboratory data, neuropsychological scores and olfactory behavior scores was performed to explore indicators related to cognitive decline and provide new insights into the etiology and classification of obese patients. Combined with clinical evaluation and imaging examination, the changes of cognitive behavior and brain structure and function in obese patients were followed up.

Conditions

• Obesity
• fMRI
• Clinical Classification

Interventions

Type	Name	Description
OTHER	Naturalistic observation	Naturalistic observation

Timeline

• Start date: 2024-10-20
• Primary completion: 2028-10-30
• Completion: 2028-10-30
• First posted: 2024-10-18
• Last updated: 2024-10-18

Locations

1 site across 1 country: China