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Not Yet RecruitingNCT06647914

Predicting Disease Progression in Atrial Fibrillation: A Multiparametric Approach for Prognostic Marker Identification and Personalized Patient Management

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
322 (estimated)
Sponsor
IRCCS Policlinico S. Donato · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This project leverages artificial intelligence (AI) to decipher Atrial Fibrillation (AF) progression and optimize treatment strategies. By recruiting a diverse cohort of 322 AF patients, we will gather a robust multiparametric dataset including clinical, genetic, electrocardiographic, and echocardiographic data. Harnessing AI, we will extract and correlate hidden components within ECG-obtained P-wave data and echocardiographic studies with atrial fibrosis, culminating in an atrial fibrosis score (AFS). The AFS will non-invasively predict fibrosis extent and AF clinical progression, including metrics like rehospitalization, cardiac morbidity, and mortality. Ultimately, this endeavor aims to improve AF patient management, significantly reducing healthcare costs, and enhancing patient quality of life.

Conditions

Timeline

Start date
2025-09-03
Primary completion
2026-03-01
Completion
2026-08-31
First posted
2024-10-18
Last updated
2024-10-18

Source: ClinicalTrials.gov record NCT06647914. Inclusion in this directory is not an endorsement.

Predicting Disease Progression in Atrial Fibrillation: A Multiparametric Approach for Prognostic Marker Identification a (NCT06647914) · Clinical Trials Directory