NCT06646406

Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 114,165 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Accepted

Summary

The study will test two tactics to improve uptake of two vaccines in adults. The vaccines prevent COVID-19 and influenza. Both are common and harmful. Most adults do not get either vaccine. This is despite strong recommendations that all adults get both vaccines. The study will involve adult patients at eight Mayo Clinic primary care practices in Rochester and Kasson. The study will test the two tactics together. Four clinics will get the two tactics. The other four clinics will not. The study will randomly assign the two tactics to the clinics. One tactic is to send a letter by US mail to the patient. The letter will state strong recommendations on getting both vaccines now. It will tell patients how to get the vaccines now. The second tactic is to send monthly emails to clinicians. It will remind them to use every visit to vaccinate patients against COVID-19 and influenza. The study will compare the uptake of the two vaccines after six months in the clinics with and without the two tactics.

Conditions

• COVID-19 Immunisation
• Influenza Vaccine

Interventions

Type	Name	Description
BEHAVIORAL	Patient letter and clinician communication	Single mailing to patients from practice with a reminder that the influenza and COVID-19 vaccines are due, and monthly emailing to the patients' clinicians with information about how to make a strong recommendation for those vaccines

Timeline

• Start date: 2024-10-21
• Primary completion: 2025-04-30
• Completion: 2025-04-30
• First posted: 2024-10-17
• Last updated: 2025-08-05

Locations

2 sites across 1 country: United States