NCT06644664

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

The Effect of Nicotine and Tobacco Message Framing on Use Among Diverse Groups of Young Adults: Aim 3 Randomized Control Trial (RCT)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 292 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This clinical trial evaluates the effect of message framing on smoking behaviors among lesbian, gay, bisexual, transgender, queer (LGBTQ+) young adults who use nicotine and/or tobacco. Tobacco regulation has contributed to a steady decline in tobacco products designed to be smoked (combustible), but there has been an increase in the use of new tobacco products, such as electronic nicotine delivery systems (ENDS). The use of more than one tobacco product (polytobacco) is high in LGBTQ+ populations. Both LGBTQ+ people and people who engage in polytobacco use are less likely to view tobacco as harmful, which may reinforce tobacco use. Message framing includes culturally targeted messages to communicate the absolute risks (AR) and relative risks (RR) of polytobacco use. Using message framing may increase quit rates or change smoking behaviors in LGBTQ+ young adults who use nicotine and/or tobacco products.

Detailed description

PRIMARY OBJECTIVES: I. Assess the feasibility of delivering mobile multimedia messaging (MMS) anti-tobacco messages developed in the K99 to LGBT young adults via texting. II. Estimate effect sizes of exposure to anti-tobacco messages on risk perceptions and tobacco use over time. OUTLINE: Participants are randomized to 1 of 3 arms. ARM I: Participants receive AR anti-polytobacco MMS messages 3 times a week (TIW) and a check-in text message once a week (QW) for a total of 6 weeks. ARM II: Participants receive RR anti-polytobacco MMS messages TIW and a check-in text message QW for a total of 6 weeks. ARM III: Participants receive control MMS messages on health risks of ultraviolet (UV)/sun exposure TIW and a check-in text message QW for a total of 6 weeks. All participants also receive smoking cessation resources via email during follow up. After completion of study intervention, participants are followed up at 6 and 12 weeks.

Conditions

• Tobacco-Related Carcinoma

Interventions

Type	Name	Description
BEHAVIORAL	Health Education	Receive control MMS messages
OTHER	Interview	Ancillary studies
BEHAVIORAL	Smoking Cessation Intervention	Receive AR MMS messages
BEHAVIORAL	Smoking Cessation Intervention	Receive RR MMS messages
BEHAVIORAL	Smoking Cessation Intervention	Receive smoking cessation resources
OTHER	Survey Administration	Ancillary studies
OTHER	Text Message-Based Navigation Intervention	Receive check-in text message

Timeline

• Start date: 2024-09-24
• Primary completion: 2026-02-02
• Completion: 2026-02-02
• First posted: 2024-10-16
• Last updated: 2026-03-30

Locations

1 site across 1 country: United States