Trials / Active Not Recruiting
Active Not RecruitingNCT06643429
Impact of Environmental Factors and Metabolomics on Colorectal Cancer.
Impact of Environmental Factors and Metabolomics on Colorectal Cancer Development and Prognosis Based on Environmental Factors and Metabolomics.
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 700 (estimated)
- Sponsor
- Dong Peng · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Colorectal cancer is one of the malignant tumours with high morbidity and mortality worldwide, posing a serious threat to human health. In recent years, the incidence of colorectal cancer has been on the rise with changes in lifestyle and dietary habits. Although some progress has been made in treatments such as surgery, chemotherapy and radiotherapy, however, the early diagnosis, prognosis assessment and personalised treatment of colorectal cancer still face great challenges. Therefore, it is of great academic value and practical significance to deeply explore the influencing factors of colorectal cancer occurrence, development and its prognosis, especially the research on environmental factors and metabolomics.
Detailed description
In this study, investigators collected clinical information, blood, urine and stool for ambient air pollution analysis, blood metabolomics analysis and stool macro-genetic sequencing by including patients from healthy control and colorectal cancer groups, respectively. Environmental factors, metabolomics and intestinal microbiota data were integrated and analysed to screen for indicators that play a key role in colorectal cancer development and construct a colorectal cancer prediction model.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | colorectal cancer | Patients diagnosed with colorectal cancer by pathological biopsy. |
| DIAGNOSTIC_TEST | colorectal neoplasm | Patients diagnosed with colorectal adenoma confirmed by colonoscopy. |
Timeline
- Start date
- 2024-10-01
- Primary completion
- 2025-10-01
- Completion
- 2027-10-01
- First posted
- 2024-10-16
- Last updated
- 2024-10-16
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06643429. Inclusion in this directory is not an endorsement.