Trials / Not Yet Recruiting
Not Yet RecruitingNCT06641245
PREconception Folic Acid Clinical Efficacy (PREFACE) Trial
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 272 (estimated)
- Sponsor
- University of British Columbia · Academic / Other
- Sex
- Female
- Age
- 19 Years – 42 Years
- Healthy volunteers
- Not accepted
Summary
A study to help understand what forms of folic acid are most effective to increase folate status during pregnancy for the best protection against neural tube defects
Detailed description
A multisite randomized controlled trial to determine whether supplementation with (6S)-5-methyltetrahydrofolic acid (5-MTHF) is at least as effective as synthetic folic acid in increasing maternal folate status for protection against neural tube defects (NTDs).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Folic Acid | folic acid (0.6 mg) |
| DIETARY_SUPPLEMENT | 5-MTHF (5-methyltetrahydrofolate) | 0.625 mg/d (6S)-5-MTHF |
Timeline
- Start date
- 2025-01-31
- Primary completion
- 2029-01-31
- Completion
- 2030-01-31
- First posted
- 2024-10-15
- Last updated
- 2024-10-21
Source: ClinicalTrials.gov record NCT06641245. Inclusion in this directory is not an endorsement.