NCT06641206

Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

Intra-articular Dexmedetomidine for Treatment of Chronic Knee Pain: A Prospective Case-Control Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 40 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to anesthesia and local anesthetics. Given its potential for pain management, exploring DEX as a treatment for KOA could offer a new and promising approach.

Conditions

• Chronic Knee Pain

Interventions

Type	Name	Description
DRUG	Triamcinolone Acetonide	1 ml of triamcinolone acetonide was used to prepare a solution for knee injection for patients with Chronic Knee Pain
DRUG	Bupivacaine Hydrochloride	20mg of bupivacaine hydrochloride was used to prepare a solution for knee injection for patients with Chronic Knee Pain
DRUG	Dexmedetomidine	Dexmedetomidine solution was prepared by mixing Dexmedetomidine in a dose of 3 µg/kg in 5-ml saline

Timeline

• Start date: 2024-09-17
• Primary completion: 2025-01-01
• Completion: 2025-03-01
• First posted: 2024-10-15
• Last updated: 2024-10-15

Locations

1 site across 1 country: Egypt