NCT06640244

The Effect of Cosmetic Face Care Products on Facial Skin Tone and Spot Brightening

A Clinical Study to Evaluate the Efficacy of Prototypes for Improvement in Skin Tone and Spot Brightening in a Full-Face Study Design

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (actual)
• Sponsor: Unilever R&D · Industry
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This is a single centre, 5-cell, blinded study to evaluate changes in even skin tone, skin glow, facial pigmented spots, and the microbiome of facial skin following the use of cosmetic face care products on the whole face over a 12 week period.

Detailed description

This is a randomized, blinded, 5 cell, full-face study designed to evaluate changes in even skin tone, skin glow, pigmented spots and the surface microbiome of facial skin following the use of one of five cosmetic face care products. This study will accept up to 50 participants per cell (250 participants overall) who meet the inclusion/exclusion criteria to ensure that at least 40 participants per cell complete the study. Participants will be randomised to receive one of the five cosmetic face care products which will be applied to the whole face using a defined protocol. If accepted onto the study, all participants will be provided with a marketed face wash to use for one week prior to the baseline visit and throughout the whole study. Visual and instrumental assessments of skin colour, skin glow and even tone will be conducted throughout the duration of the study (12 weeks product use and 6 weeks regression). Non-invasive skin surface samples will be collected at several timepoints for evaluation of the skin microbiome.

Conditions

• Pigment Spots

Interventions

Type	Name	Description
OTHER	Sunscreen	To be used by all participants throughout the study
OTHER	Cosmetic product G18	Cosmetic face care product
OTHER	Cosmetic product N70	Cosmetic face care product
OTHER	Cosmetic product D79	Cosmetic face care product
OTHER	Cosmetic product E84	Cosmetic face care product
OTHER	Cosmetic product C68	Cosmetic face care product

Timeline

• Start date: 2024-10-22
• Primary completion: 2025-11-13
• Completion: 2025-11-13
• First posted: 2024-10-15
• Last updated: 2025-11-17

Locations

1 site across 1 country: India