NCT06640036

FILIP: Fat Intake, Inflammation and LIPids

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Göteborg University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Low-grade inflammation is involved in the pathogenesis of type 2 diabetes and cardiovascular disease. Increasing evidence suggests that dietary intake may be involved in the inflammatory process. How nutritional composition of the diet affects the inflammatory response is however not well understood. The aim of this project is to study if intake of three different fat sources induce different effects on inflammation markers, blood lipids, blood glucose and the microbiota.

Conditions

• Cardiometabolic Risk Factors
• Inflammation
• Microbiota

Interventions

Type	Name	Description
OTHER	Rapeseed oil	During 1 week, 46 % of total energy intake will come from rapeseed oil, using pre-prepared and blinded meals.
OTHER	Butter	During 1 week, 46 % of total energy intake will come from butter, using pre-prepared and blinded meals.
OTHER	Coconut oil	During 1 week, 46 % of total energy intake will come from coconut oil, using pre-prepared and blinded meals.

Timeline

• Start date: 2025-04-08
• Primary completion: 2025-12-17
• Completion: 2025-12-17
• First posted: 2024-10-15
• Last updated: 2026-02-04

Locations

1 site across 1 country: Sweden