Trials / Completed
CompletedNCT06636708
Efficacy of Nanodropper-mediated Topical Anesthetic
Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Proparacaine HCl
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 56 (actual)
- Sponsor
- Columbia University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The goal of this clinical trial is to compare the onset and duration of numbness of the surface of the eye following the administration of numbing drops, called proparacaine, using either a standard eye drop bottle or a "Nanodropper" adaptor. The Nanodropper is designed to administer smaller-sized drops, or microdrops. Participants will: 1. Complete a baseline eye exam. 2. Receive a numbing drop using a standard dropper in one eye and the Nanodropper in the other eye. 3. Have their eyes tested for numbness at specific time points (30 seconds, 1, 2, 5, and 10 minutes after getting the drops). 4. Tell the researchers if they feel pain during the eye sensation tests. 5. Complete a survey about their experience with the eyedrops and testing procedure. This study could help us find a way to use less medication while still effectively administering eye medications, potentially saving money and reducing medical waste.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| COMBINATION_PRODUCT | Nanodropper and Proparacaine HCl 0.5% | The Nanodropper is an eyedrop bottle adaptor that creates smaller eyedrops by coupling to an existing eyedrop bottle. This intervention involves the administration of proparacaine HCl 0.5% using the Nanodropper. |
| COMBINATION_PRODUCT | Standard Eye Drop Bottle with Proparacaine HCl 0.5% | This intervention involves administration of proparacaine HCl 0.5% using a standard eye drop bottle. |
Timeline
- Start date
- 2024-12-12
- Primary completion
- 2025-04-24
- Completion
- 2025-04-24
- First posted
- 2024-10-15
- Last updated
- 2026-02-12
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06636708. Inclusion in this directory is not an endorsement.